Analytical Data
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Gene name
ZNHIT3
- Application
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Alternative Names
ZNHIT3；TRIP3；Zinc finger HIT domain-containing Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15649
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Expression Region
1-155aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMASLKCS TVVCVICLEK PKYRCPACRV PYCSVVCFRK HKEQCNPETR PVEKKIRSAL PTKTVKPVEN KDDDDSIADF LNSDEEEDRV SLQNLKNLGE SATLRSLLLN PHLRQLMVNL DQGEDKAKLM RAYMQEPLFV EFADCCLGIV EPSQNEES
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Molecular Weight
20 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNHIT3, a member of the ZNFX1-like family, has garnered attention due to its potential role in various biological processes and diseases. Initially identified as a nuclear protein with zinc finger domains, ZNHIT3 is believed to be implicated in regulating gene expression and maintaining genomic stability. Recent studies have linked alterations in ZNHIT3 expression to different types of cancers, suggesting that it may function as a tumor suppressor or oncogene depending on the cellular context. Its involvement in immune response regulation has also been highlighted, particularly in the context of autoimmune diseases and infections. Understanding the functional mechanisms of ZNHIT3 is essential for elucidating its biological significance and potential therapeutic implications. The recombinant protein form of ZNHIT3 is crucial for these investigations, as it enables detailed analysis of its structure, interactions, and functional properties. By producing ZNHIT3 in a laboratory setting, researchers aim to explore its binding partners, post-translational modifications, and overall impact on cellular pathways. This research not only deepens our comprehension of ZNHIT3's role in health and disease but also paves the way for developing novel diagnostic and therapeutic strategies targeting this protein.
