Analytical Data
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基因名
B3GALTL
- Application
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别名
B3GLCT; B3GALTL; B3GTLBeta-1.3-glucosyltransferase; Beta3Glc-T; EC 2.4.1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6Y288
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表达区间
21-498aa
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氨基酸序列
MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQHLLSCYDSGKPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQVPISFHKHWNIDPVKVYFTWLAPSDEDKARQETQKGFREEL
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分子量
83 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
B3GALTL, or Beta-1,3-galactosyltransferase-like protein, is a crucial enzyme involved in the biosynthesis of glycoproteins and glycolipids, primarily through the transfer of galactose residues. Studies have shown that B3GALTL plays a significant role in various biological processes, including cell adhesion, immune response, and developmental pathways. Deficiencies or mutations in the B3GALTL gene have been linked to several congenital disorders, particularly those affecting brain and nerve development. Given its pivotal role in glycosylation pathways, researchers have been increasingly interested in B3GALTL as a potential biomarker for certain diseases and as a target for therapeutic interventions. The recombinant expression of B3GALTL in various systems allows for the detailed study of its enzymatic characteristics and substrate specificity, facilitating a better understanding of its biological functions. Additionally, characterizing the protein can provide insights into its potential roles in disease mechanisms, paving the way for innovative treatments based on glycoengineering. With advancements in biotechnology, the production of recombinant B3GALTL not only supports fundamental research but also offers practical applications in drug development and personalized medicine.
