Analytical Data
-
Gene name
PGPEP1
- Application
-
Alternative Names
2810003H13Rik; 5 oxoprolyl peptidase; 5-oxoprolyl-peptidase; FLJ20208; MGC10812; PAP I; PAP-I; PAPI; Pcp; PGI; pGlu peptidase I; PGP; PGP I; PGP-I; Pgpep1; PGPI; PGPI_HUMAN; Pyroglutamyl aminopeptidase I; Pyroglutamyl peptidase 1; pyroglutamyl peptidase I; Pyroglutamyl-peptidase 1; Pyroglutamyl-peptidase I; pyrrolidone carboxylate peptidase; Pyrrolidone-carboxylate peptidase
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NXJ5
-
Expression Region
1-209 aa
-
AA Sequence
MEQPRKAVVV TGFGPFGEHT VNASWIAVQE LEKLGLGDSV DLHVYEIPVE YQTVQRLIPA LWEKHSPQLV VHVGVSGMAT TVTLEKCGHN KGYKGLDNCR FCPGSQCCVE DGPESIDSII DMDAVCKRVT TLGLDVSVTI SQDAGRYLCD FTYYTSLYQS HGRSAFVHVP PLGKPYNADQ LGRALRAIIE EMLDLLEQSE GKINYCHKH
-
Molecular Weight
23.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PGPEP1, a recombinant protein derived from a specific genetic construct, has garnered attention in the field of molecular biology and biotechnology due to its potential applications in various therapeutic and diagnostic processes. The protein is an enhanced version of a naturally occurring peptidase that plays a crucial role in regulating peptide homeostasis and is involved in critical biological processes, such as immune response and protein degradation. The study of PGPEP1's structure and function provides insights into its enzymatic mechanisms and substrate specificity, making it a valuable target for drug development, particularly in treating diseases associated with peptide dysregulation, such as cancer and autoimmune disorders. Researchers focus on employing techniques like recombinant DNA technology, protein purification, and enzymatic assays to explore the properties of PGPEP1, which can lead to breakthroughs in understanding its functionality. Additionally, advancements in synthetic biology and protein engineering offer possibilities for designing novel variants of PGPEP1 with enhanced activity or specificity. As a result, PGPEP1 not only contributes to fundamental biological knowledge but also holds promise in the realm of therapeutic interventions, thereby emphasizing the importance of ongoing research in this area.
