Analytical Data
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基因名
MRPS4
- Application
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别名
MRPS4；C15orf12；MRPS4；U3 small nucleolar ribonucleoProtein Protein IMP3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NV31
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表达区间
1-184aa
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氨基酸序列
MVRKLKFHEQ KLLKQVDFLN WEVTDHNLHE LRVLRRYRLQ RREDYTRYNQ LSRAVRELAR RLRDLPERDQ FRVRASAALL DKLYALGLVP TRGSLELCDF VTASSFCRRR LPTVLLKLRM AQHLQAAVAF VEQGHVRVGP DVVTDPAFLV TRSMEDFVTW VDSSKIKRHV LEYNEERDDF DLEA
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分子量
21.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPS4, or Mitochondrial Ribosomal Protein S4, is an essential component of the mitochondrial ribosome, playing a crucial role in mitochondrial protein synthesis and, consequently, cellular energy production. Research into MRPS4 has gained traction due to its involvement in various mitochondrial diseases and its potential implications in broader metabolic disorders. Mitochondria are often referred to as the “powerhouses of the cell,” and any dysfunction in the protein synthesis machinery can lead to impaired cellular function and contribute to pathologies, including neurodegenerative diseases and aging. Moreover, MRPS4 has been highlighted for its potential role in cell signaling and the regulation of apoptosis, which further underscores its significance in cellular health. The study of MRPS4 and its interactions with other mitochondrial components provides insight into the underlying mechanisms of mitochondrial dysfunction, paving the way for the development of targeted therapies. Understanding how MRPS4 is regulated and its precise functions may also open avenues for innovative treatment strategies in mitochondrial diseases and cancer, where mitochondrial metabolism is often altered. As the field of mitochondrial research expands, MRPS4 stands out as a key protein that could provide valuable information on both basic biology and potential clinical applications.
