Analytical Data
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基因名
b3GAT1
- Application
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别名
b3GAT1；GLCATP；GalactosylgalactosylxylosylProtein 3-beta-glucuronosyltransferase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P2W7
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表达区间
28-334aa
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氨基酸序列
TLAPLLAVHK DEGSDPRRET PPGADPREYC TSDRDIVEVV RTEYVYTRPP PWSDTLPTIH VVTPTYSRPV QKAELTRMAN TLLHVPNLHW LVVEDAPRRT PLTARLLRDT GLNYTHLHVE TPRNYKLRGD ARDPRIPRGT MQRNLALRWL RETFPRNSSQ PGVVYFADDD NTYSLELFEE MRSTRRVSVW PVAFVGGLRY EAPRVNGAGK VVGWKTVFDP HRPFAIDMAG FAVNLRLILQ RSQAYFKLRG VKGGYQESSL LRELVTLNDL EPKAANCTKI LVWHTRTEKP VLVNEGKKGF TDPSVEI
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分子量
62 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
B3GAT1, also known as Beta-1,3-glucuronyltransferase 1, is an important enzyme involved in glycosaminoglycan biosynthesis, particularly in the formation of specific glycan structures that are crucial for cellular functions and signaling. Mutations in the B3GAT1 gene have been linked to various developmental disorders, including skeletal dysplasias and neurological impairments, making it a significant target for biomedical research. Understanding the structure and function of B3GAT1, especially through the study of its recombinant protein, can provide insights into its enzymatic mechanism and substrate specificity. The generation of B3GAT1 recombinant proteins enables researchers to elucidate the enzyme's role in glycosylation processes, investigate its functional consequences in disease models, and explore potential therapeutic interventions. Additionally, the study of B3GAT1 may contribute to the broader understanding of glycosylation in human health and disease, highlighting its relevance in developing novel diagnostic and therapeutic strategies for conditions associated with glycan deficiencies. Overall, the research into B3GAT1 and its recombinant protein forms opens exciting avenues for advancing our knowledge of glycosylation biology and its implications for human diseases.
