Analytical Data
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基因名
PEX7
- Application
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别名
PBD9B; PCDP1; Peroxin 7; Peroxin-7; Peroxisomal PTS2 receptor; Peroxisomal targeting signal 2 receptor; Peroxisome biogenesis factor 7; Peroxisome targeting signal 2 receptor; PEX7; PEX7 protein; PEX7_HUMAN; PTS2 receptor; PTS2R; RCDP1; RD
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00628
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表达区间
1-323 aa
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氨基酸序列
MSAVCGGAAR MLRTPGRHGY AAEFSPYLPG RLACATAQHY GIAGCGTLLI LDPDEAGLRL FRSFDWNDGL FDVTWSENNE HVLITCSGDG SLQLWDTAKA AGPLQVYKEH AQEVYSVDWS QTRGEQLVVS GSWDQTVKLW DPTVGKSLCT FRGHESIIYS TIWSPHIPGC FASASGDQTL RIWDVKAAGV RIVIPAHQAE ILSCDWCKYN ENLLVTGAVD CSLRGWDLRN VRQPVFELLG HTYAIRRVKF SPFHASVLAS CSYDFTVRFW NFSKPDSLLE TVEHHTEFTC GLDFSLQSPT QVADCSWDET IKIYDPACLT IPA
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分子量
35.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PEX7 is a pivotal protein involved in the peroxisomal biogenesis process, specifically recognized for its role as a receptor for the import of peroxisomal matrix proteins. Research into PEX7 and its function is critical because defects in this pathway can lead to various peroxisomal disorders, such as Zellweger syndrome and other related conditions, which are characterized by the improper functioning of peroxisomes and can result in severe developmental and metabolic consequences. The study of PEX7 is further fueled by the need to understand the molecular mechanisms underlying peroxisomal protein import, as well as the potential for therapeutic interventions in diseases caused by PEX7 deficiencies. Recent advancements in structural biology and biochemistry techniques have allowed researchers to elucidate the molecular interactions between PEX7 and its ligands, enhancing our understanding of the import mechanism and identifying potential targets for drug development. Understanding PEX7's structure and function may also shed light on its evolutionary significance across different species, thereby contributing to the broader field of cell biology and organelle function. Overall, PEX7 represents a crucial focus of research that bridges basic science and clinical implications, aiming to clarify its multifaceted roles in cellular physiology and its potential impact on treating peroxisomal disorders.
