Analytical Data
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Gene name
TOR1AIP1
- Application
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Alternative Names
TOR1AIP1；LAP1；Torsin-1A-interacting Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5JTV8
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Expression Region
1-583aa
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AA Sequence
MAGDGRRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTRMQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEVETTAVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKLEVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKFTNSNTPNSYNHMDPDKLNGLWSRISHLVLPVQPENALKRGICL
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Molecular Weight
66.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TOR1AIP1, or TOR1A Interacting Protein 1, is a key protein involved in various cellular processes, particularly in the context of neurobiology and cellular signaling. Its unique interaction with the TOR1A protein, which is associated with the regulation of neurotransmitter release and the maintenance of neuronal function, has sparked considerable research interest. Mutations and dysregulation of TOR1AIP1 have been implicated in neurological disorders such as torquetenial dystonia, highlighting its potential role in the pathophysiology of these conditions. The study of TOR1AIP1 as a recombinant protein allows researchers to explore its structure, function, and interactions in detail, paving the way for understanding its biological significance and therapeutic potential. By examining the recombinant form of TOR1AIP1, scientists aim to uncover insights into its molecular mechanisms, which could ultimately contribute to the development of targeted therapies for related disorders and enhance our understanding of neuronal health and disease. Additionally, investigating the protein's interactions at the molecular level may provide a clearer picture of how it contributes to synaptic function and stability, thus making it a crucial focus for advancing neurobiological research.
