Analytical Data
-
基因名
PEX11B
- Application
-
别名
PEX11B; Peroxisomal membrane protein 11B; Peroxin-11B; Peroxisomal biogenesis factor 11B; Protein PEX11 homolog beta; PEX11-beta
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O96011
-
表达区间
1-259 aa
-
氨基酸序列
MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVHLSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRLKGSGGGVPGGSETGGLGGPGTPGGGLPQLALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTLIYPWLRLKP
-
分子量
54.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human ATP2B1 Protein，GST
Cat：PA2000-5684
Recombinant Human PRKACa Protein，His
Cat：PA2000-1609
Protein Description
PEX11B is a member of the PEX11 family of peroxisomal biogenesis factors that play a crucial role in the regulation of peroxisome proliferation. Peroxisomes are essential organelles involved in various metabolic processes, including lipid metabolism and the detoxification of reactive oxygen species. Dysregulation of peroxisome dynamics has been linked to several human diseases, such as Zellweger syndrome and other peroxisomal biogenesis disorders. The study of PEX11B is particularly significant because it is involved in the fission of peroxisomes and has been implicated in the adaptive response of cells to metabolic stress. Understanding the molecular mechanisms underlying PEX11B function could provide insights into how peroxisome dynamics are altered in disease states and potentially reveal novel therapeutic targets. Recent research has focused on the structural and functional characterization of PEX11B, exploring its interactions with other proteins and its role in signaling pathways that regulate peroxisome biogenesis. The recombinant expression of PEX11B allows for in-depth biochemical studies, making it a valuable tool for elucidating its function and contributions to cellular homeostasis. This growing body of research underlines the importance of PEX11B in both fundamental cellular processes and its potential implications in health and disease.
