Analytical Data
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基因名
PEX11A
- Application
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别名
PEX11A; PEX11; Peroxisomal membrane protein 11A; HsPEX11p; 28 kDa peroxisomal integral membrane protein; PMP28; Peroxin-11A; Peroxisomal biogenesis factor 11A; Protein PEX11 homolog alpha; PEX11-alpha
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75192
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表达区间
1-247 aa
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氨基酸序列
MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR
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分子量
54.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PEX11A, a member of the PEX11 protein family, plays a crucial role in the regulation of peroxisome proliferation and function. Peroxisomes are vital organelles involved in lipid metabolism and detoxification processes, contributing to cellular homeostasis and metabolism. The study of PEX11A has intensified due to its involvement in various physiological and pathological conditions, including metabolic disorders and neurodegenerative diseases. Research suggests that PEX11A facilitates peroxisome division and replication, thereby influencing cellular responses to oxidative stress and fatty acid metabolism. Understanding the mechanisms underlying PEX11A function and its regulatory pathways is essential for elucidating its role in maintaining peroxisome homeostasis. Investigations into PEX11A also have potential therapeutic implications, as modulating its activity may provide strategies to combat diseases linked to peroxisomal dysfunction. This makes PEX11A a significant target for research within the fields of cell biology and medicine, aiming to uncover new insights into peroxisomal dynamics and their connection to overall cellular health.
