Cat: PA2000-1603

Recombinant Human OXM Protein,His

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Analytical Data

  • Gene name

    OXM

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    OXM;Olfactory receptor 51M1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P01275

  • Expression Region

    53-89aa

  • AA Sequence

    HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIA

  • Molecular Weight

    6.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

OXM (Oxyntomodulin) is a peptide hormone produced in the intestines, primarily known for its role in regulating appetite and glucose metabolism. It is derived from proglucagon, alongside other important peptides like glucagon and GLP-1. The interest in OXM has surged due to its dual action in promoting satiety while simultaneously enhancing insulin sensitivity, making it a potential therapeutic target for obesity and type 2 diabetes. Research into OXM recombinant proteins aims to explore their physiological effects, molecular mechanisms, and potential applications in metabolic disorders. Studies have indicated that OXM can impact energy expenditure and body weight regulation, highlighting its relevance in the context of obesity management. Furthermore, the exploration of OXM as an avenue for drug development has led to advancements in understanding its receptor interactions and signaling pathways. These insights are crucial for developing OXM-based therapies with improved efficacy and reduced side effects. Overall, the OXM recombinant protein research holds promise for providing new strategies in the treatment of metabolic diseases, as well as enhancing our understanding of hormonal regulation of energy balance.

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