Analytical Data
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基因名
PDXDC2
- Application
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别名
PDXDC2P; PDXDC2; Putative pyridoxal-dependent decarboxylase domain-containing protein 2; EC 4.1.1.-; pyridoxal-dependent decarboxylase domain-containing 2 pseudogene
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P474
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表达区间
1-469 aa
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氨基酸序列
MDASLEKIAD PTLAEMGKNL KEAVKMLEDS QRRTEEENGK KLISRDIPGP LQGSGQDMVS ILQLVQNLMH GDEDEEPQSP RIQNIGEQGH VAVLGHSLGA YILTLDEEKL RKLTTRILSD TTLWLCRIFR YENGCAYFHE EEREGLAKIC RLAIHSQYED FVVDGFSGLY NKKPVIYLSA AARPGLGQYL CNQLGLPFPC LCRVPCNTMF GSQHQMDVAF LEKLIKDDIE RGRLPLLLVA NAGTAAVGHT DKIGRLKELC EQYGIWLHVE GVNLATLALG YVSSSVLAAA KCDSMTMTPG PWLGLPAVPA VTLYKHDPAL TLVAGLISNK PTDKLRALPL WLSLQYLGLD GFVERIKHAC QLSQWLQESL KKVNYIKILV EDELSSPVVV FRFFQELPGS DPVFKAVPVP NMTPSAVGRE RHSCDALNLW LGEQLKQLVP ASGLTVMDLE AEGTCLRFSP LMTAAGMIS
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分子量
51.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PDXDC2 (Pyridoxal-5'-phosphate dependent decarboxylase 2) is a protein that has attracted attention due to its role in biogenic amine synthesis, particularly in the decarboxylation of various amino acids. Understanding the structure and function of PDXDC2 is crucial for elucidating its biochemical pathways and potential implications in neurological and metabolic disorders. Emerging studies suggest that PDXDC2 may influence neurotransmitter levels, which can impact mood regulation and cognitive functions. Research has focused on the enzyme's catalytic mechanisms, substrate specificity, and regulatory effects within cellular environments. Moreover, the potential for PDXDC2 as a therapeutic target in conditions associated with disrupted amine metabolism has led to significant interest. As scientists develop recombinant forms of this protein, they aim to analyze its properties in vitro, facilitating a deeper understanding of its physiological roles and paving the way for novel therapeutic interventions. The recombinant PDXDC2 can serve as a valuable tool in drug discovery and enzymology research, providing insights into how disturbances in such metabolic pathways can lead to health issues. Additionally, the development of assays to measure PDXDC2 activity could help in screening for compounds that specifically modulate its function, thereby offering new avenues for treatment strategies in psychiatric and neurodegenerative diseases. Through ongoing research, the importance of PDXDC2 is becoming increasingly evident, with potential ramifications for both basic science and clinical applications.
