Analytical Data
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基因名
ASTN2
- Application
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别名
Astn2; ASTN2_HUMAN; Astrotactin 2; Astrotactin-2; bA264C15.1; bA67K19.1; KIAA0634
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75129
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表达区间
1-440aa
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氨基酸序列
MNTLLCKGMFCLLSWEADSRGRLGEYTLQPLSLQTEETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKIMCEEKMVSMARNTYGESKGR
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分子量
76 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ASTN2 (Astrotactin 2) is a protein that plays a crucial role in neurodevelopment and neuronal migration. It is primarily expressed in the central nervous system and is thought to be involved in the guidance of neurons during brain development. Research has indicated that mutations or dysregulations in the ASTN2 gene are associated with various neurodevelopmental disorders, including schizophrenia and autism spectrum disorders. As a result, understanding the structure and function of ASTN2 has become a significant focus in neuroscience. Recombinant ASTN2 proteins are utilized in various studies to elucidate the molecular mechanisms underlying neuronal migration and to investigate how alterations in this protein contribute to neurodevelopmental disorders. By producing and analyzing ASTN2 recombinant proteins, researchers aim to uncover its interactions with other cellular components and to explore its potential as a target for therapeutic interventions. This research not only enhances our understanding of brain development but also paves the way for developing strategies to address neurodevelopmental conditions linked to ASTN2 dysfunction. As such, the study of ASTN2 recombinant proteins stands at the intersection of molecular biology, neurobiology, and clinical research, highlighting its significance in advancing our knowledge of complex neurological phenomena.
