Cat: PA2000-1583

Recombinant Human FOXF2 Protein,His

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Analytical Data

  • Gene name

    FOXF2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FOXF2;FKHL6;FREAC2;Forkhead box Protein F2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q12947

  • Expression Region

    1-444aa

  • AA Sequence

    MTTEGGPPPA PLRRACSPVP GALQAALMSP PPAAAAAAAA APETTSSSSS SSSASCASSS SSSNSASAPS AACKSAGGGG AGAGSGGAKK ASSGLRRPEK PPYSYIALIV MAIQSSPSKR LTLSEIYQFL QARFPFFRGA YQGWKNSVRH NLSLNECFIK LPKGLGRPGK GHYWTIDPAS EFMFEEGSFR RRPRGFRRKC QALKPMYHRV VSGLGFGASL LPQGFDFQAP PSAPLGCHSQ GGYGGLDMMP AGYDAGAGAP SHAHPHHHHH HHVPHMSPNP GSTYMASCPV PAGPGGVGAA GGGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK QPPALTPSSN PAASAGLHSS MSSYSLEQSY LHQNAREDLS VGLPRYQHHS TPVCDRKDFV LNFNGISSFH PSASGSYYHH HHQSVCQDIK PCVM

  • Molecular Weight

    45.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

FOXF2 (Forkhead Box F2) is a transcription factor belonging to the Fox gene family, which plays a crucial role in various physiological processes, including organogenesis, development, and regulation of metabolic pathways. The significance of FOXF2 is highlighted by its involvement in several biological functions, particularly in the differentiation of various cell types and its implications in diseases such as cancer and fibrotic disorders. The study of FOXF2 recombinant proteins has gained momentum in recent years due to its potential therapeutic applications and as a biomarker for certain diseases. Research indicates that FOXF2 can modulate gene expression patterns that are critical for cellular response to environmental signals, thereby influencing cellular behavior in both normal and pathological contexts. Additionally, FOXF2 has been implicated in the regulation of inflammation, making it a target for exploring novel anti-inflammatory therapies. The generation of recombinant FOXF2 proteins allows researchers to delve deeper into the mechanistic roles of this transcription factor, providing insights into its interactions with other proteins and its impact on transcriptional networks. Overall, the study of FOXF2 recombinant proteins represents a promising frontier in understanding cellular dynamics and developing targeted therapeutic strategies for diseases associated with FOXF2 dysregulation.

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