Analytical Data
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基因名
FOXF2
- Application
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别名
FOXF2；FKHL6；FREAC2；Forkhead box Protein F2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q12947
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表达区间
1-444aa
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氨基酸序列
MTTEGGPPPA PLRRACSPVP GALQAALMSP PPAAAAAAAA APETTSSSSS SSSASCASSS SSSNSASAPS AACKSAGGGG AGAGSGGAKK ASSGLRRPEK PPYSYIALIV MAIQSSPSKR LTLSEIYQFL QARFPFFRGA YQGWKNSVRH NLSLNECFIK LPKGLGRPGK GHYWTIDPAS EFMFEEGSFR RRPRGFRRKC QALKPMYHRV VSGLGFGASL LPQGFDFQAP PSAPLGCHSQ GGYGGLDMMP AGYDAGAGAP SHAHPHHHHH HHVPHMSPNP GSTYMASCPV PAGPGGVGAA GGGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK QPPALTPSSN PAASAGLHSS MSSYSLEQSY LHQNAREDLS VGLPRYQHHS TPVCDRKDFV LNFNGISSFH PSASGSYYHH HHQSVCQDIK PCVM
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分子量
45.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOXF2 (Forkhead Box F2) is a transcription factor belonging to the Fox gene family, which plays a crucial role in various physiological processes, including organogenesis, development, and regulation of metabolic pathways. The significance of FOXF2 is highlighted by its involvement in several biological functions, particularly in the differentiation of various cell types and its implications in diseases such as cancer and fibrotic disorders. The study of FOXF2 recombinant proteins has gained momentum in recent years due to its potential therapeutic applications and as a biomarker for certain diseases. Research indicates that FOXF2 can modulate gene expression patterns that are critical for cellular response to environmental signals, thereby influencing cellular behavior in both normal and pathological contexts. Additionally, FOXF2 has been implicated in the regulation of inflammation, making it a target for exploring novel anti-inflammatory therapies. The generation of recombinant FOXF2 proteins allows researchers to delve deeper into the mechanistic roles of this transcription factor, providing insights into its interactions with other proteins and its impact on transcriptional networks. Overall, the study of FOXF2 recombinant proteins represents a promising frontier in understanding cellular dynamics and developing targeted therapeutic strategies for diseases associated with FOXF2 dysregulation.
