Analytical Data
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Gene name
ULBP2
- Application
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Alternative Names
ULBP2；N2DL2；UL16-binding Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZM5
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Expression Region
26-217aa
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AA Sequence
GRADPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVS PLGKKLNVTT AWKAQNPVLREVVDILTEQLRDIQLENYTPKEPLTLQARMSCEQKAEGHS SGSWQFSFDG QIFLLFDSEKRMWTTVHPGARKMKEKWENDKVVAMSFHYFSMGDCIGWLE DFLMGMDSTL EPSAGAPLAMSSVDHHHHHH
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Molecular Weight
23 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ULBP2 (UL16-binding protein 2) is a member of the ULBP family, which plays a significant role in the immune response, particularly in the activation of natural killer (NK) cells. ULBP2 interacts with the NKG2D receptor on NK cells and some T cells, serving as a signal for these immune effectors to recognize and eliminate stressed, infected, or transformed cells. Due to its crucial involvement in immune surveillance, ULBP2 has garnered interest in cancer research, as many tumors exploit mechanisms to downregulate ULBP2 expression, thereby evading immune detection. The study of recombinant ULBP2 proteins aims to elucidate their structure-function relationships, investigate their potential as therapeutic agents, and enhance our understanding of NK cell activation. Additionally, recombinant ULBP2 could serve as a valuable tool for developing immunotherapies or vaccines that leverage the immune system's ability to target and eliminate malignant cells. Thus, the ongoing research into ULBP2 and its recombinant forms holds promise for advancing therapeutic strategies in oncology and improving our comprehension of immune regulation.
