Analytical Data
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基因名
PDSS2
- Application
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别名
All-trans-decaprenyl-diphosphate synthase subunit 2; bA59I9.3; C6orf210; Candidate tumor suppressor protein; chromosome 6 open reading frame 210; Decaprenyl pyrophosphate synthase subunit 2; decaprenyl pyrophosphate synthetase subunit 2 ; Decaprenyl-diphosphate synthase subunit 2; DLP1; DLP1_HUMAN; hDLP1; Pdss2; prenyl (decaprenyl) diphosphate synthase; subunit 2; subunit 2 of decaprenyl diphosphate synthase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86YH6
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表达区间
1-399 aa
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氨基酸序列
MNFRQLLLHL PRYLGASGSP RRLWWSPSLD TISSVGSWRG RSSKSPAHWN QVVSEAEKIV GYPTSFMSLR CLLSDELSNI AMQVRKLVGT QHPLLTTARG LVHDSWNSLQ LRGLVVLLIS KAAGPSSVNT SCQNYDMVSG IYSCQRSLAE ITELIHIALL VHRGIVNLNE LQSSDGPLKD MQFGNKIAIL SGDFLLANAC NGLALLQNTK VVELLASALM DLVQGVYHEN STSKESYITD DIGISTWKEQ TFLSHGALLA KSCQAAMELA KHDAEVQNMA FQYGKHMAMS HKINSDVQPF IKEKTSDSMT FNLNSAPVVL HQEFLGRDLW IKQIGEAQEK GRLDYAKLRE RIKAGKGVTS AIDLCRYHGN KALEALESFP PSEARSALEN IVFAVTRFS
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分子量
44.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PDSS2 (Prenyl Diphosphate Synthase Subunit 2) is a crucial enzyme involved in the biosynthesis of isoprenoids, a large class of organic compounds essential for various biological processes. Isoprenoids play significant roles in cellular functions, contributing to the formation of hormones, vitamins, and other vital biomolecules. Mutations in the PDSS2 gene can lead to various metabolic disorders, highlighting its importance in maintaining cellular health. The study of PDSS2 recombinant proteins is pivotal for understanding its structure-function relationship, enzymatic mechanism, and the implications of genetic variations on its activity. By producing PDSS2 as a recombinant protein, researchers can conduct detailed biochemical assays, structural analyses, and interaction studies, providing valuable insights into the enzyme's role in the isoprenoid biosynthetic pathway. Furthermore, understanding PDSS2's function may reveal potential therapeutic targets for diseases linked to isoprenoid metabolism. This research is not only fundamental in advancing our knowledge of metabolic pathways but also holds promise for drug development and personalized medicine approaches targeting metabolic disorders associated with PDSS2 dysfunction.
