Analytical Data
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基因名
PDLIM2
- Application
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别名
FLJ34715; MYSTIQUE; OTTHUMP00000162522; OTTHUMP00000205197; OTTHUMP00000205198; OTTHUMP00000205199; OTTHUMP00000205200; OTTHUMP00000205202; OTTHUMP00000205203; PDLI2_HUMAN; Pdlim2; PDZ and LIM domain 2 (mystique); PDZ and LIM domain protein 2; PDZ-LIM protein mystique; SLIM ; Stat-interacting LIM protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96JY6
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表达区间
1-352 aa
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氨基酸序列
MALTVDVAGP APWGFRITGG RDFHTPIMVT KVAERGKAKD ADLRPGDIIV AINGESAEGM LHAEAQSKIR QSPSPLRLQL DRSQATSPGQ TNGDSSLEVL ATRFQGSVRT YTESQSSLRS SYSSPTSLSP RAGSPFSPPP SSSSLTGEAA ISRSFQSLAC SPGLPAADRL SYSGRPGSRQ AGLGRAGDSA VLVLPPSPGP RSSRPSMDSE GGSLLLDEDS EVFKMLQENR EGRAAPRQSS SFRLLQEALE AEERGGTPAF LPSSLSPQSS LPASRALATP PKLHTCEKCS TSIANQAVRI QEGRYRHPGC YTCADCGLNL KMRGHFWVGD ELYCEKHARQ RYSAPATLSS RA
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分子量
37.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PDLIM2 (PDZ and LIM domain 2) is a member of the PDZ-LIM protein family, which plays critical roles in various biological processes, including cell signaling, cytoskeletal organization, and transcriptional regulation. Recent studies have highlighted PDLIM2's involvement in cancer biology, where it functions as a tumor suppressor in certain contexts and may also promote tumor progression in others. This dual role is attributed to PDLIM2's interaction with various signaling pathways, including those related to growth factor receptors and oncogenes, making it a potential biomarker for cancer diagnosis and prognosis. Furthermore, PDLIM2 has been implicated in immune responses and cardiac development. Given its significance in both normal physiology and pathological conditions, the recombinant expression of PDLIM2 protein has gained attention for functional studies and therapeutic developments. Researchers focus on characterizing its structure and understanding the molecular mechanisms underlying its activities. Utilizing recombinantly produced PDLIM2 enables detailed investigation of its interactions and functions in vitro, thus paving the way for novel therapeutic strategies that exploit its regulatory roles in tumors and other diseases.
