Analytical Data
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基因名
ASB4
- Application
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别名
Ankyrin repeat and SOCS box containing 4; Ankyrin repeat and SOCS box containing Protein 4
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y574
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表达区间
1-319aa
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氨基酸序列
MKLKAILIQRQIDVDTVFEVEDENMVLASYKQGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLVCRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVRLCPVVSRLRKIQMAALSEISK
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分子量
61.49 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ASB4 (Ankyrin Repeat and SOCS Box-containing Protein 4) is a member of the ASB family, which plays a crucial role in various cellular processes, including signal transduction and protein degradation via the ubiquitin-proteasome pathway. Research has shown that ASB4 is involved in regulating important biological functions, such as immune responses, cell differentiation, and apoptosis. Its unique structure, characterized by ankyrin repeats, suggests a potential role in protein-protein interactions, which may influence cellular signaling pathways and substrate specificity for ubiquitination. Recent studies have highlighted the significance of ASB4 in cancer biology, where alterations in its expression and functionality could impact tumorigenesis and metastasis. Understanding the molecular mechanisms governing ASB4 activity can provide insights into its contributions to diseases and may open avenues for therapeutic interventions. The recombinant expression of ASB4 in various systems aims to elucidate its biological functions, interactions with other proteins, and the consequences of its dysregulation, thus serving as a foundation for more targeted research in cell biology and oncology.
