Analytical Data
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Gene name
PCTP
- Application
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Alternative Names
PC TP; PC-TP; PCTP; Phosphatidylcholine transfer protein; PPCT_HUMAN; StAR related lipid transfer (START) domain containing 2; StAR related lipid transfer protein 2; StAR-related lipid transfer protein 2; STARD 2; StARD2; START domain containing 2; START domain containing protein 2; START domain-containing protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKL6
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Expression Region
1-214 aa
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AA Sequence
MELAAGSFSE EQFWEACAEL QQPALAGADW QLLVETSGIS IYRLLDKKTG LYEYKVFGVL EDCSPTLLAD IYMDSDYRKQ WDQYVKELYE QECNGETVVY WEVKYPFPMS NRDYVYLRQR RDLDMEGRKI HVILARSTSM PQLGERSGVI RVKQYKQSLA IESDGKKGSK VFMYYFDNPG GQIPSWLINW AAKNGVPNFL KDMARACQNY LKKT
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Molecular Weight
24.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of PCTP (Phosphatidylcholine Transfer Protein) recombinant proteins has gained significant attention due to their critical role in cellular lipid transport and metabolism. PCTP is involved in the transfer of phosphatidylcholine between membranes, which is essential for various cellular processes, including membrane biogenesis, signaling, and the regulation of lipid composition. Dysfunctions in lipid transport mechanisms have been linked to a range of diseases, including obesity, cardiovascular disorders, and neurodegenerative conditions. Research into PCTP recombinant proteins allows for a clearer understanding of the molecular mechanisms underlying lipid transfer and metabolism. These proteins serve as valuable tools for elucidating the pathways involved in phospholipid dynamics and for exploring potential therapeutic targets. Advances in recombinant DNA technology have enabled the production of PCTP in various host systems, providing insights into its structure-function relationships. Furthermore, purifying and characterizing recombinant PCTP can lead to the identification of small molecules that may modulate its activity, offering potential avenues for drug discovery. Overall, the investigation of PCTP recombinant proteins is crucial not only for fundamental lipid biology but also for its implications in health and disease, making it a prominent area of research in biochemistry and molecular biology.
