Analytical Data
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基因名
ARR3
- Application
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别名
ARR3; ARR4; ARRC_HUMAN; Arrestin 3 retinal; Arrestin 3 retinal (X-arrestin); Arrestin 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P36575
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表达区间
1-388aa
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氨基酸序列
MSKVFKKTSS NGKLSIYLGK RDFVDHVDTV EPIDGVVLVD PEYLKCRKLF VMLTCAFRYG RDDLEVIGLT FRKDLYVQTL QVVPAESSSP QGPLTVLQER LLHKLGDNAY PFTLQMVTNL PCSVTLQPGP EDAGKPCGID FEVKSFCAEN PEETVSKRDY VRLVVRKVQF APPEAGPGPS AQTIRRFLLS AQPLQLQAWM DREVHYHGEP ISVNVSINNC TNKVIKKIKI SVDQITDVVL YSLDKYTKTV FIQEFTETVA ANSSFSQSFA VTPILAASCQ KRGLALDGKL KHEDTNLASS TIIRPGMDKE LLGILVSYKV RVNLMVSCGG ILGDLTASDV GVELPLVLIH PKPSHEAASS EDIVIEEFTR KGEEESQKAV EAEGDEGS
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The ARR3 protein, a member of the amphibian retinoic acid-receptor-related orphan receptor family, has garnered significant attention in recent years due to its potential roles in various biological processes. Initially identified in Xenopus laevis, ARR3 is involved in cellular signaling pathways that regulate developmental processes, cellular differentiation, and responses to environmental stimuli. Its unique property as an orphan receptor, which means it lacks a known natural ligand, poses intriguing questions regarding its function and mechanisms of action. Recent studies have suggested that ARR3 may play a critical role in the retina, particularly in photoreceptor cell signaling, thus implicating it in vision-related pathways. Furthermore, aberrations in ARR3 expression or function have been associated with several diseases, including retinal disorders and cancers. Consequently, understanding the structural and functional dynamics of ARR3 is crucial not only for elucidating its biological roles but also for exploring its therapeutic potential. Researchers are employing various techniques, including molecular cloning, protein expression, and site-directed mutagenesis, to investigate the interactions and pathways influenced by ARR3. This growing body of research aims to uncover the intricate mechanisms through which ARR3 operates, providing valuable insights into its contribution to health and disease, and potentially leading to innovative strategies for intervention in related conditions. As the field advances, ongoing efforts will be essential to fully characterize the implications of ARR3 in both basic and applied sciences, further promoting its significance within the broader context of cellular signaling research.












