Analytical Data
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Gene name
UBE2H
- Application
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Alternative Names
UBE2H；Ubiquitin-conjugating enzyme E2 H
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62256
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Expression Region
1-183aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSSPSPG KRRMDTDVVK LIESKHEVTI LGGLNEFVVK FYGPQGTPYE GGVWKVRVDL PDKYPFKSPS IGFMNKIFHP NIDEASGTVC LDVINQTWTA LYDLTNIFES FLPQLLAYPN PIDPLNGDAA AMYLHRPEEY KQKIKEYIQK YATEEALKEQ EEGTGDSSSE SSMSDFSEDE AQDMEL
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Molecular Weight
23 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UBE2H is a member of the ubiquitin-conjugating enzyme family, playing a crucial role in the ubiquitin-proteasome system, which is essential for protein degradation and cellular regulation. Research into UBE2H has garnered interest due to its involvement in various cellular processes, including cell cycle regulation, DNA repair, and response to oxidative stress. Aberrations in UBE2H function have been linked to several diseases, particularly cancers, where altered ubiquitination patterns can affect tumor growth and progression. The generation of recombinant UBE2H protein facilitates a deeper understanding of its biochemical properties and interactions with ubiquitin ligases and other cellular substrates. Thus, studying UBE2H through recombinant protein techniques not only enhances the understanding of its functional mechanisms but also opens avenues for developing targeted therapeutic strategies to manipulate ubiquitin signaling pathways in disease contexts.
