Analytical Data
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基因名
ARPC1A
- Application
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别名
ARC1A_HUMAN; Arc40; ARPC1A; Epididymis luminal Protein 68; Epididymis secretory Protein Li 307
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92747
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表达区间
1-370aa
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氨基酸序列
MSLHQFLLEP ITCHAWNRDR TQIALSPNNH EVHIYKKNGS QWVKAHELKE HNGHITGIDW APKSDRIVTC GADRNAYVWS QKDGVWKPTL VILRINRAAT FVKWSPLENK FAVGSGARLI SVCYFESEND WWVSKHIKKP IRSTVLSLDW HPNNVLLAAG SCDFKCRVFS AYIKEVDEKP ASTPWGSKMP FGQLMSEFGG SGTGGWVHGV SFSASGSRLA WVSHDSTVSV ADASKSVQVS TLKTEFLPLL SVSFVSENSV VAAGHDCCPM LFNYDDRGCL TFVSKLDIPK QSIQRNMSAM ERFRNMDKRA TTEDRNTALE TLHQNSITQV SIYEVDKQDC RKFCTTGIDG AMTIWDFKTL ESSIQGLRIM
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分子量
66.44 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARPC1A, a subunit of the Arp2/3 complex, plays a crucial role in actin dynamics and cytoskeletal organization in eukaryotic cells. This protein is essential for the nucleation of new actin filaments, which is vital for various cellular processes, including cell motility, division, and shape maintenance. Dysregulation of ARPC1A has been associated with several diseases, including cancer, where altered actin polymerization contributes to increased cell migration and invasion. Consequently, the study of recombinant ARPC1A protein has garnered significant interest in the field of cell biology and therapeutic development. Researchers are particularly focused on understanding the structural and functional properties of ARPC1A to elucidate its role in actin filament assembly and to explore its potential as a target for pharmacological intervention. The production of recombinant ARPC1A allows for detailed biochemical assays, structural characterization, and the investigation of interactions with other cellular proteins. This research not only enhances our understanding of the fundamental mechanisms of the cytoskeleton but also paves the way for developing strategies to manipulate actin dynamics in disease contexts, thus presenting a promising avenue for innovative therapeutic approaches.
