Cat: PA2000-1531

Recombinant Human SOX14 Protein,His

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Analytical Data

  • 基因名

    SOX14

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SOX14;SOX28;Transcription factor SOX-14

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O95416

  • 表达区间

    1-240aa

  • 氨基酸序列

    MSKPSDHIKR PMNAFMVWSR GQRRKMAQEN PKMHNSEISK RLGAEWKLLS EAEKRPYIDE AKRLRAQHMK EHPDYKYRPR RKPKNLLKKD RYVFPLPYLG DTDPLKAAGL PVGASDGLLS APEKARAFLP PASAPYSLLD PAQFSSSAIQ KMGEVPHTLA TGALPYASTL GYQNGAFGSL SCPSQHTHTH PSPTNPGYVV PCNCTAWSAS TLQPPVAYIL FPGMTKTGID PYSSAHATAM

  • 分子量

    26.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SOX14, a member of the SRY (Sex-determining Region Y)-related HMG-box (SOX) family of transcription factors, plays a crucial role in various biological processes, including embryonic development and cell differentiation. Research on SOX14 has gained momentum due to its potential implications in neurodevelopmental disorders and its involvement in the regulation of key genes during neuronal differentiation. Recent studies have shown that SOX14 can influence the expression of genes associated with neural progenitor cell maintenance and differentiation, suggesting that it may serve as a critical regulator in the development of the nervous system. Furthermore, mutations in the SOX14 gene have been linked to specific neurodevelopmental conditions, underscoring the importance of understanding its functional mechanisms. The production of recombinant SOX14 protein has become essential for elucidating its biochemical properties and interactions with other cellular components. By employing techniques such as protein expression and purification, researchers aim to investigate the structural and functional characteristics of SOX14, paving the way for future therapeutic strategies targeting SOX14-related pathways. This ongoing research underscores the significance of SOX14 in developmental biology and its potential as a biomarker for neurodevelopmental disorders, thereby advancing our understanding of complex genetic and environmental interactions in brain development. As the exploration of SOX14 continues, it holds promise for unveiling new insights into its roles in both normal development and disease, ultimately contributing to the field of molecular biology and genetics.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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