Cat: PA2000-5607

Recombinant Human ARL6IP6 Protein,GST

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Analytical Data

  • Gene name

    ARL6IP6

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ARL6IP6; PFAAP1; ADP-ribosylation factor-like Protein 6-interacting Protein 6

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N6S5

  • Expression Region

    1-226aa

  • AA Sequence

    MSFAESGWRSALRRRGPGTPGPVARPSYSSFTQGDSWGEGEVDEEEGCDQVARDLRAEFSAGAWSEPRKRSVLPPDGNGSPVLPDKRNGIFPAAAGSRAQPRRWPVQVLSILCSLLFAILLAFLLAIAYLIVKELHAENLKNEDDVDTGLLGFWTLLIISLTAGFSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCLM

  • Molecular Weight

    51.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ARL6IP6, a member of the Arf-like protein family, has garnered attention in recent years due to its potential role in regulating intracellular processes such as membrane trafficking and cytoskeletal dynamics. Understanding the function of ARL6IP6 is crucial, as dysregulation of similar GTPases has been implicated in various diseases, including cancer and neurodegenerative disorders. Recent studies suggest that ARL6IP6 may be involved in the modulation of autophagy and cellular stress responses, highlighting its significance in maintaining cellular homeostasis. Furthermore, its expression patterns in different tissues and developmental stages suggest it may have distinct roles in various biological contexts. The recombinant protein of ARL6IP6 serves as a valuable tool for elucidating its molecular interactions and functional mechanisms. Research utilizing this recombinantly expressed protein can provide insights into its GTP-binding properties, interaction with associated proteins, and influence on cellular signaling pathways. By dissecting the structural and functional characteristics of ARL6IP6, researchers aim to unveil its contribution to cellular physiology and pathology, paving the way for therapeutic strategies targeting related pathways.

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