Analytical Data
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Gene name
TXNL4A
- Application
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Alternative Names
TXNL4A;KIAA1178;CD2 antigen cytoplasmic tail-binding Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P83876
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Expression Region
1-142aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSYMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY
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Molecular Weight
19 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TXNL4A, or Thioredoxin-like 4A, is a protein that belongs to the thioredoxin family, which plays critical roles in cell proliferation, apoptosis, and redox signaling. Research has indicated that TXNL4A is involved in various cellular processes, including the regulation of protein folding and the maintenance of cellular homeostasis. Overexpression of TXNL4A has been associated with certain cancers, suggesting that it may act as an oncoprotein, contributing to tumorigenesis and progression. Additionally, TXNL4A has shown potential as a therapeutic target because of its influence on the redox state within cells, which can affect cancer cell survival and resistance to chemotherapy. Previous studies highlighted the protein's interactions with other cellular components and its role in modulating stress responses, making it a subject of interest for understanding disease mechanisms. The recombinant expression of TXNL4A is crucial for biochemical studies and potential drug development, allowing scientists to explore its structure, function, and interactions in detail. This research may pave the way for novel therapeutic strategies aimed at targeting TXNL4A-related pathways in cancer and other diseases, enhancing our understanding of its biological significance and providing insights into potential interventions.











