Cat: PA2000-5604

Recombinant Human ARL6IP2 Protein,His

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Analytical Data

  • Gene name

    ARL6IP2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Atl2; Arl6ip2; Atlastin-2; ADP-ribosylation factor-like Protein 6-interacting Protein 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NHH9

  • Expression Region

    1-412aa

  • AA Sequence

    MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD

  • Molecular Weight

    71.06 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ARL6IP2, a member of the Arf-like family of small GTPases, has garnered attention due to its potential role in cellular processes and disease mechanisms. This protein is implicated in various cellular functions, including endosomal trafficking, signal transduction, and cell proliferation. Research has suggested that ARL6IP2 may play a significant role in the regulation of the immune response and is associated with several conditions, including cancer and neurodegenerative diseases. Its expression levels and activity can be influenced by various stimuli, hinting at its dynamic role in cellular homeostasis. To further understand ARL6IP2’s function and its implications in health and disease, researchers focus on producing recombinant ARL6IP2. This involves utilizing molecular cloning techniques to express the protein in suitable host systems, allowing for its characterization, structural analysis, and assessment of its interaction with other cellular components. By elucidating the mechanistic pathways in which ARL6IP2 is involved, scientists aim to identify potential therapeutic targets and biomarkers for diseases where ARL6IP2 is dysregulated. Overall, the study of ARL6IP2 recombinant protein represents an important step towards unraveling its biological roles and therapeutic potentials in various pathologies.

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