Analytical Data
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基因名
PAXIP1
- Application
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别名
CAGF 28; CAGF 29; CAGF28; CAGF29; FLJ41049; PACIP 1; PACIP1; PAX interacting (with transcription activation domain) protein 1; PAX interacting protein 1; PAX transactivation activation domain-interacting protein; PAX transcription activation domain interacting protein 1 like; PAX-interacting protein 1; PAXI1_HUMAN; PAXIP 1; PAXIP 1L; paxip1; PAXIP1 protein; PAXIP1L; Protein encoded by CAG trinucleotide repeats; PTIP; TNRC 2; TNRC2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZW49
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表达区间
1-757 aa
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氨基酸序列
MAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVTAHWLNTVLKKKKMVPPHRALHFPVAFPPGGKPCSQHIISVTGFVDSDRDDLKLMAYLAGAKYTGYLCRSNTVLICKEPTGLKYEKAKEWRIPCVNAQWLGDILLGNFEALRQIQYSRYTAFSLQDPFAPTQHLVLNLLDAWRVPLKVSAELLMSIRLPPKLKQNEVANVQPSSKRARIEDVPPPTKKLTPELTPFVLFTGFEPVQVQQYIKKLYILGGEVAESAQKCTHLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNYILRDAEAEVLFSFSLEESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSKQPSFRKLMEHKQNSSLSEIILISCENDLHLCREYFARGIDVHNAEFVLTGVLTQTLDYESYKFN
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分子量
113.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
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Protein Description
PAXIP1, or PAX interacting protein 1, is a crucial protein that serves as a co-activator in the regulation of gene expression, particularly in pathways involving the PAX (Paired Box) family of transcription factors. Given the vital role of PAX proteins in development and differentiation, their interaction with PAXIP1 has sparked interest in understanding the underlying molecular mechanisms and their implications in various diseases, including cancers and genetic disorders. Recent studies have indicated that PAXIP1 influences cellular proliferation, apoptosis, and differentiation, highlighting its potential as a therapeutic target. The exploration of PAXIP1 recombinantly expressed in laboratory settings allows researchers to elucidate its functional properties, protein interactions, and the effects of its modulation in biological systems. By employing techniques such as gene cloning, expression in heterologous systems, and biochemical assays, scientists aim to uncover how PAXIP1 contributes to cellular processes and its potential role in pathology. The recombinant protein's study facilitates the development of targeted strategies in translational medicine and enhances our understanding of the complex regulatory networks involving PAX transcription factors.
