Analytical Data
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Gene name
TSSK2
- Application
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Alternative Names
TSSK2；DGSG；Testis-specific serine/threonine-Protein kinase 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96PF2
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Expression Region
1-358aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMDDATVL RKKGYIVGIN LGKGSYAKVK SAYSERLKFN VAVKIIDRKK TPTDFVERFL PREMDILATV NHGSIIKTYE IFETSDGRIY IIMELGVQGD LLEFIKCQGA LHEDVARKMF RQLSSAVKYC HDLDIVHRDL KCENLLLDKD FNIKLSDFGF SKRCLRDSNG RIILSKTFCG SAAYAAPEVL QSIPYQPKVY DIWSLGVILY IMVCGSMPYD DSDIRKMLRI QKEHRVDFPR SKNLTCECKD LIYRMLQPDV SQRLHIDEIL SHSWLQPPKP KATSSASFKR EGEGKYRAEC KLDTKTGLRP DHRPDHKLGA KTQHRLLVVP ENENRMEDRL AETSRAKDHH ISGAEVGKAS T
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Molecular Weight
43 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TSSK2, or Testis-Specific Serine Kinase 2, is a member of the testis-specific serine/threonine kinase family, which plays a crucial role in spermatogenesis and male fertility. The study of TSSK2 and its recombinant protein is significant due to its potential implications in male reproductive health and associated disorders. Research indicates that TSSK2 is predominantly expressed in the testis and is involved in the regulation of sperm development and motility. Aberrant expression or mutations in the TSSK2 gene have been linked to infertility issues, making it an important target for understanding the molecular mechanisms underlying reproductive dysfunction. The creation of recombinant TSSK2 enables researchers to investigate its biochemical properties, interact with various substrates, and elucidate its role in signaling pathways critical for spermatogenesis. Moreover, understanding TSSK2's function can pave the way for developing novel diagnostic tools or therapeutic strategies for addressing male infertility. These studies also contribute to our broader knowledge of kinases in reproductive biology, enhancing our understanding of the complexities of male reproductive health. Thus, research on TSSK2 recombinant protein holds significant promise for advancing both basic science and clinical applications in reproductive medicine.
