Analytical Data
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Gene name
TAS1R1
- Application
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Alternative Names
TAS1R1；GPR70；T1R1；TR1；Taste receptor type 1 member 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7RTX1
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Expression Region
21-567aa
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AA Sequence
FACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERMQCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMVLGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSSNQLCRECQAFMAHTMPKLKAFSMSSAYNAYRAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTS
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Molecular Weight
68.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The TAS1R1 gene encodes a critical component of the sweet taste receptor, which is part of the larger TAS1R family responsible for taste perception. The TAS1R1 protein forms a heterodimer with TAS1R3 to facilitate the recognition and transduction of sweet and umami tastes, playing a significant role in dietary preferences and nutrition. Understanding the function of TAS1R1 and its interactions within the taste signaling pathways is vital, as it influences food intake and can be linked to metabolic disorders and obesity. Research involving recombinant TAS1R1 protein is crucial for elucidating its structural and functional properties, as well as its associated signaling mechanisms. By expressing and purifying this protein, scientists can conduct assays to investigate its binding affinities with various ligands, including amino acids and sweeteners, and to explore its role in cellular signaling processes. This research has implications for developing better strategies in food science, nutrition, and public health, particularly concerning managing taste-related issues and improving dietary practices. Additionally, studies on TAS1R1 provide insights into evolutionary adaptations in taste perception across different species, highlighting the broader implications of taste receptor research in understanding organismal behavior and ecology. Overall, investigating TAS1R1 recombinant protein serves as a fundamental step in unveiling the complexities of taste biology and its impact on human health.
