Analytical Data
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Gene name
TSHb
- Application
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Alternative Names
TSHb；Thyrotropin subunit beta
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P01222
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Expression Region
21-132aa
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AA Sequence
FCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSY
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Molecular Weight
28.9kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on TSHb recombinant protein is centered around the role of Thyroid-Stimulating Hormone (TSH) in regulating thyroid function and its implications in various health conditions. TSH, produced by the pituitary gland, stimulates the thyroid gland to produce thyroid hormones, which are crucial for metabolism, growth, and development. Abnormalities in TSH levels can lead to thyroid disorders such as hypothyroidism or hyperthyroidism, affecting millions worldwide. The recombinant form of TSH, derived through biotechnological methods, allows researchers to explore its biochemical properties, signaling pathways, and therapeutic potential with greater precision. This approach not only enhances our understanding of thyroid physiology but also paves the way for developing targeted treatments for thyroid-related diseases. Additionally, TSHb recombinant protein studies can lead to advancements in diagnostic tools, enabling better monitoring of thyroid function in clinical settings. Overall, the exploration of TSHb through recombinant technology represents a significant step forward in endocrinology and offers promising avenues for therapeutic intervention and improved patient care in thyroid disorders.
