Analytical Data
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Gene name
TPM4
- Application
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Alternative Names
TPM4；Tropomyosin alpha-4 chain
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P67936
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Expression Region
1-248aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TPM4 (Tropomyosin 4) is a member of the tropomyosin family of proteins, known for their role in stabilizing and regulating actin filaments in various cellular processes. Research on TPM4 has gained attention due to its involvement in critical functions such as cell motility, muscle contraction, and intracellular transport. This protein is characterized by its ability to bind to actin and form coiled-coil structures, which contribute to the structural integrity of the cytoskeleton. Recent studies suggest that TPM4 is not only vital for maintaining cellular architecture but also plays a significant role in signaling pathways that affect cell proliferation and apoptosis. Furthermore, aberrations in TPM4 expression have been linked to various pathological conditions, including cancers and cardiovascular diseases, highlighting its potential as a therapeutic target. Consequently, the recombinant expression of TPM4 has become an important area of research, facilitating detailed studies on its structure-function relationships, regulatory mechanisms, and interactions with other cellular proteins. The production of recombinant TPM4 provides valuable insights into its biochemical properties and enables the exploration of its role in health and disease, paving the way for novel therapeutic strategies.
