Analytical Data
-
基因名
PABPC5
- Application
-
别名
PABPC5; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly(A)-binding protein 5
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96DU9
-
表达区间
1-382 aa
-
氨基酸序列
MGSGEPNPAG KKKKYLKAAL YVGDLDPDVT EDMLYKKFRP AGPLRFTRIC RDPVTRSPLG YGYVNFRFPA DAEWALNTMN FDLINGKPFR LMWSQPDDRL RKSGVGNIFI KNLDKSIDNR ALFYLFSAFG NILSCKVVCD DNGSKGYAYV HFDSLAAANR AIWHMNGVRL NNRQVYVGRF KFPEERAAEV RTRDRATFTN VFVKNIGDDI DDEKLKELFC EYGPTESVKV IRDASGKSKG FGFVRYETHE AAQKAVLDLH GKSIDGKVLY VGRAQKKIER LAELRRRFER LRLKEKSRPP GVPIYIKNLD ETINDEKLKE EFSSFGSISR AKVMMEVGQG KGFGVVCFSS FEEATKAVDE MNGRIVGSKP LHVTLGQARR RC
-
分子量
43.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PABPC5 (Poly(A)-Binding Protein Cytoplasmic 5) is a member of the poly(A)-binding protein family, which plays critical roles in mRNA metabolism, stability, and translation regulation. Understanding PABPC5 is particularly important because it is involved in the cellular response to stress and regulates the fate of mRNAs during various physiological processes. Recent studies have suggested that PABPC5 may have implications in cancer biology and other diseases, as its expression levels can influence tumor progression and the response to treatment. Given its significant role in cell biology, the development of recombinant protein for PABPC5 has become a focal point of research. The production of PABPC5 recombinant protein allows for detailed functional studies and structural analyses, facilitating insights into its interaction with RNA and other binding partners. Furthermore, investigating PABPC5's role in post-transcriptional regulation might reveal potential therapeutic targets or biomarkers for diseases where its dysregulation is implicated. Thus, the research on PABPC5 recombinant protein is driven by a need to understand its mechanistic functions, contributions to cellular processes, and potential as a therapeutic target in human health. This research not only aims to elucidate the fundamental biology of PABPC5 but also to explore its application in genomic medicine and therapeutic interventions.
