Analytical Data
-
基因名
P2RY6
- Application
-
别名
P2RY6; PP2891; P2Y purinoceptor 6; P2Y6
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q15077
-
表达区间
1-328 aa
-
氨基酸序列
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL FYFTQKKFRRRPHELLQKLTAKWQRQGR
-
分子量
36.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
P2RY6, a member of the purinergic receptor family, is a G protein-coupled receptor that primarily responds to the nucleotide ATP, playing crucial roles in various physiological and pathological processes. Research has indicated that P2RY6 is involved in regulating immune responses, neuronal signaling, and tissue repair mechanisms. Dysregulation of this receptor is associated with several diseases, including autoimmune disorders and neurodegenerative conditions. The study of recombinant P2RY6 proteins has gained significance as it provides insights into the receptor's structure-function relationships, signaling pathways, and potential as a therapeutic target. By producing and characterizing recombinant P2RY6, researchers are able to investigate its interactions with ligands, identify allosteric sites, and develop novel pharmacological agents that could modulate its activity. Furthermore, understanding P2RY6’s role in cell signaling can pave the way for innovative treatment strategies for various diseases, emphasizing the importance of recombinant P2RY6 protein research in the broader context of drug discovery and molecular biology.
