Analytical Data
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Gene name
TP53I3
- Application
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Alternative Names
TP53I3；PIG3；Quinone oxidoreductase PIG3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q53FA7
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Expression Region
1-332aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MLAVHFDKPG GPENLYVKEV AKPSPGEGEV LLKVAASALN RADLMQRQGQ YDPPPGASNI LGLEASGHVA ELGPGCQGHW KIGDTAMALL PGGGQAQYVT VPEGLLMPIP EGLTLTQAAA IPEAWLTAFQ LLHLVGNVQA GDYVLIHAGL SGVGTAAIQL TRMAGAIPLV TAGSQKKLQM AEKLGAAAGF NYKKEDFSEA TLKFTKGAGV NLILDCIGGS YWEKNVNCLA LDGRWVLYGL MGGGDINGPL FSKLLFKRGS LITSLLRSRD NKYKQMLVNA FTEQILPHFS TEGPQRLLPV LDRIYPVTEI QEAHKYMEAN KNIGKIVLEL PQ
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Molecular Weight
38 kD
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TP53I3, also known as the Tumor Protein p53 Inducible Protein 3, is a gene that has garnered significant interest in cancer research due to its role in the cellular response to stress and its association with the tumor suppressor protein p53. The protein encoded by TP53I3 is involved in various biological processes, including apoptosis, cell cycle regulation, and the response to DNA damage, which positions it as a critical player in maintaining genomic integrity. Research has shown that TP53I3 is upregulated in response to p53 activation, suggesting its potential role as a mediator of the p53 pathway. Alterations in TP53I3 expression have been linked to various types of cancers, making it a candidate for further exploration in cancer diagnostics and therapeutics. Additionally, studies have suggested that TP53I3 may influence cellular metabolism and oxidative stress responses, contributing to tumor progression and therapies' efficacy. Given the pivotal role of p53 in cancer biology, understanding TP53I3's function and mechanism can provide insights into tumorigenesis and highlight its potential as a biomarker or therapeutic target in cancer management. Continued investigations into the TP53I3 protein could yield valuable information for developing novel strategies in cancer treatment, particularly in tumors exhibiting p53 dysfunction. The evolving research surrounding TP53I3 underscores its importance in the broader context of oncogenic processes and underscores the need for further studies to elucidate its precise role in cancer biology.
