Cat: PA2000-5561

Recombinant Human ARFRP1 Protein,His

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Analytical Data

  • Gene name

    ARFRP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ARFRP_HUMAN; ARFRP1; ARL 18; ARL18; ARP 1; ARP; ARP1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q13795

  • Expression Region

    1-201aa

  • AA Sequence

    MYTLLSGLYK YMFQKDEYCI LILGLDNAGK TTFLEQSKTR FNKNYKGMSL SKITTTVGLN IGTVDVGKAR LMFWDLGGQE ELQSLWDKYY AECHGVIYVI DSTDEERLAE SKQAFEKVVT SEALCGVPVL VLANKQDVET CLSIPDIKTA FSDCTSKIGR RDCLTQACSA LTGKGVREGI EWMVKCVVRN VHRPPRQRDI T

  • Molecular Weight

    22.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ARFRP1, a member of the ARF (ADP-ribosylation factor) family, plays a crucial role in various cellular processes, including vesicular trafficking, cytoskeletal dynamics, and cell signaling. Research on ARFRP1 has gained momentum as its dysregulation has been associated with several diseases, including cancer and neurodegenerative disorders. Studies indicate that ARFRP1 is involved in membrane traffic, particularly in the formation and transport of vesicles within the cell, which is essential for maintaining cellular homeostasis and communication. The protein exhibits a unique distribution in tissues and is thought to interact with multiple binding partners, making it a potential target for therapeutic intervention. Understanding the structural and functional characteristics of ARFRP1 through recombinant protein expression can provide insights into its mechanism of action and role in disease pathology. Furthermore, the study of ARFRP1 may contribute to the development of novel strategies for modulating its function, offering potential avenues for the treatment of diseases linked to its dysfunction. Thus, investigating ARFRP1's properties and interactions at the molecular level is vital for uncovering its biological significance and therapeutic potential.

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