Analytical Data
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Gene name
ARFRP1
- Application
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Alternative Names
ARFRP_HUMAN; ARFRP1; ARL 18; ARL18; ARP 1; ARP; ARP1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13795
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Expression Region
1-201aa
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AA Sequence
MYTLLSGLYK YMFQKDEYCI LILGLDNAGK TTFLEQSKTR FNKNYKGMSL SKITTTVGLN IGTVDVGKAR LMFWDLGGQE ELQSLWDKYY AECHGVIYVI DSTDEERLAE SKQAFEKVVT SEALCGVPVL VLANKQDVET CLSIPDIKTA FSDCTSKIGR RDCLTQACSA LTGKGVREGI EWMVKCVVRN VHRPPRQRDI T
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Molecular Weight
22.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARFRP1, a member of the ARF (ADP-ribosylation factor) family, plays a crucial role in various cellular processes, including vesicular trafficking, cytoskeletal dynamics, and cell signaling. Research on ARFRP1 has gained momentum as its dysregulation has been associated with several diseases, including cancer and neurodegenerative disorders. Studies indicate that ARFRP1 is involved in membrane traffic, particularly in the formation and transport of vesicles within the cell, which is essential for maintaining cellular homeostasis and communication. The protein exhibits a unique distribution in tissues and is thought to interact with multiple binding partners, making it a potential target for therapeutic intervention. Understanding the structural and functional characteristics of ARFRP1 through recombinant protein expression can provide insights into its mechanism of action and role in disease pathology. Furthermore, the study of ARFRP1 may contribute to the development of novel strategies for modulating its function, offering potential avenues for the treatment of diseases linked to its dysfunction. Thus, investigating ARFRP1's properties and interactions at the molecular level is vital for uncovering its biological significance and therapeutic potential.











