Analytical Data
-
基因名
APOBEC3H
- Application
-
别名
MALLTAETFR LQFNNKRRLR RPYYPRKALL CYQLTPQNGS TPTRGYFENK KKCHAEICFI NEIKSMGLDE TQCYQVTCYL TWSPCSSCAW ELVDFIKAHD HLNLGIFASR LYYHWCKPQQ KGLRLLCGSQ VPVEVMGFPK FADCWENFVD HEKPLSFNPY KMLEELDKNS RAIKRRLERI KIPGVRAQGR YMDILCDAEV
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6NTF7
-
表达区间
1-200aa
-
氨基酸序列
MALLTAETFR LQFNNKRRLR RPYYPRKALL CYQLTPQNGS TPTRGYFENK KKCHAEICFI NEIKSMGLDE TQCYQVTCYL TWSPCSSCAW ELVDFIKAHD HLNLGIFASR LYYHWCKPQQ KGLRLLCGSQ VPVEVMGFPK FADCWENFVD HEKPLSFNPY KMLEELDKNS RAIKRRLERI KIPGVRAQGR YMDILCDAEV
-
分子量
23.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
APOBEC3H is a member of the APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family of proteins, which are primarily known for their ability to edit RNA and DNA, thereby playing crucial roles in immune defense against viral infections, particularly those involving retroviruses such as HIV. Research on APOBEC3H has gained significance due to its polymorphic nature and the functional variability it exhibits in different populations, which may influence susceptibility to infections and disease progression. This protein is found to possess cytidine deaminase activity, enabling it to induce mutations in viral genomes, thus hampering viral replication. However, its evolutionary dynamics, including its potential to facilitate viral escape through hypermutation, also present a double-edged sword. Understanding the mechanisms governing APOBEC3H function and its interaction with viruses is essential for developing antiviral strategies and could provide insights into the broader implications of host-pathogen interactions. As researchers continue to investigate its role, the recombinant expression of APOBEC3H protein becomes vital for elucidating its functional properties, structural characteristics, and possible therapeutic applications, offering a promising avenue to enhance our understanding of innate immunity and viral pathogenesis.
