Analytical Data
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Gene name
TLR2
- Application
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Alternative Names
TLR2；TIL4；Toll-like receptor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60603
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Expression Region
19-588aa
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AA Sequence
KEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYIS NSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSS WFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRK DFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFV DVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQ VMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLS ENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNI DISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNN LNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQ LDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPS HVRGQQVQDVRLSVSECHRTLEHHHHHH
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Molecular Weight
66 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Toll-like receptor 2 (TLR2) is a crucial component of the innate immune system, playing a significant role in the recognition of various pathogens, including bacteria, viruses, and fungi. It functions by detecting specific molecular patterns associated with these pathogens, thereby initiating immune responses that help in combating infections. Research on TLR2 recombinant proteins has gained prominence due to their potential applications in vaccine development and immunotherapy. By producing TLR2 as a recombinant protein, scientists can investigate its structure, function, and interaction with various ligands, leading to a deeper understanding of how it influences immune responses. Additionally, TLR2 is involved in the inflammatory process, making it a target for therapeutic interventions in autoimmune diseases and chronic inflammatory conditions. The use of TLR2 recombinant proteins also allows for the exploration of their adjuvant capabilities in vaccine formulations, enhancing the efficacy of vaccines by promoting stronger immune responses. As a result, the study of TLR2 recombinant proteins has significant implications for developing new strategies in infectious disease prevention and treatment, as well as in managing inflammatory disorders. The ongoing research in this area continues to uncover the complexities of TLR2-mediated signaling pathways, paving the way for innovative approaches in immunology and personalized medicine.
