Analytical Data
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基因名
TLR2
- Application
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别名
TLR2；TIL4；Toll-like receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60603
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表达区间
19-588aa
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氨基酸序列
KEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYIS NSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSS WFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRK DFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFV DVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQ VMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLS ENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNI DISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNN LNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQ LDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPS HVRGQQVQDVRLSVSECHRTLEHHHHHH
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分子量
66 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Toll-like receptor 2 (TLR2) is a crucial component of the innate immune system, playing a significant role in the recognition of various pathogens, including bacteria, viruses, and fungi. It functions by detecting specific molecular patterns associated with these pathogens, thereby initiating immune responses that help in combating infections. Research on TLR2 recombinant proteins has gained prominence due to their potential applications in vaccine development and immunotherapy. By producing TLR2 as a recombinant protein, scientists can investigate its structure, function, and interaction with various ligands, leading to a deeper understanding of how it influences immune responses. Additionally, TLR2 is involved in the inflammatory process, making it a target for therapeutic interventions in autoimmune diseases and chronic inflammatory conditions. The use of TLR2 recombinant proteins also allows for the exploration of their adjuvant capabilities in vaccine formulations, enhancing the efficacy of vaccines by promoting stronger immune responses. As a result, the study of TLR2 recombinant proteins has significant implications for developing new strategies in infectious disease prevention and treatment, as well as in managing inflammatory disorders. The ongoing research in this area continues to uncover the complexities of TLR2-mediated signaling pathways, paving the way for innovative approaches in immunology and personalized medicine.
