Cat: PA2000-5512

Recombinant Human ANKS1A Protein,GST

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Analytical Data

  • Gene name

    ANKS1A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q92625

  • Expression Region

    1-460aa

  • AA Sequence

    MSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

  • Molecular Weight

    77.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ANKS1A, or Ankyrin Repeat and Suppressor of Cytokine Signaling 1A, is a protein that has garnered interest due to its potential role in various cellular processes, particularly in the regulation of immune responses and cellular signaling pathways. Research has suggested that ANKS1A may be involved in the modulation of inflammatory responses, impacting the pathogenesis of several diseases, including autoimmune disorders and cancers. Its ankyrin repeat motif indicates potential interactions with a variety of cellular proteins, positioning ANKS1A as a key player in maintaining cellular homeostasis and signaling integrity. Recent studies have focused on the recombinant expression of ANKS1A to elucidate its structure-function relationships and to define its interactions with other signaling molecules. By generating recombinant ANKS1A proteins, researchers aim to better understand its biological functions and regulatory mechanisms, paving the way for therapeutic applications. Additionally, investigating ANKS1A in the context of disease models could provide insights into its potential as a biomarker or a target for novel treatments. The exploration of ANKS1A thus holds promise for advancing our knowledge of immune regulation and its implications in health and disease.

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