Analytical Data
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基因名
ANKS1A
- Application
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别名
ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92625
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表达区间
1-460aa
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氨基酸序列
MSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
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分子量
77.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ANKS1A, or Ankyrin Repeat and Suppressor of Cytokine Signaling 1A, is a protein that has garnered interest due to its potential role in various cellular processes, particularly in the regulation of immune responses and cellular signaling pathways. Research has suggested that ANKS1A may be involved in the modulation of inflammatory responses, impacting the pathogenesis of several diseases, including autoimmune disorders and cancers. Its ankyrin repeat motif indicates potential interactions with a variety of cellular proteins, positioning ANKS1A as a key player in maintaining cellular homeostasis and signaling integrity. Recent studies have focused on the recombinant expression of ANKS1A to elucidate its structure-function relationships and to define its interactions with other signaling molecules. By generating recombinant ANKS1A proteins, researchers aim to better understand its biological functions and regulatory mechanisms, paving the way for therapeutic applications. Additionally, investigating ANKS1A in the context of disease models could provide insights into its potential as a biomarker or a target for novel treatments. The exploration of ANKS1A thus holds promise for advancing our knowledge of immune regulation and its implications in health and disease.
