Analytical Data
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Gene name
TGFB3
- Application
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Alternative Names
TGFB3；Transforming growth factor beta-3 proProtein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P10600
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Expression Region
301-412aa
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AA Sequence
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
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Molecular Weight
16.7kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Transforming growth factor-beta 3 (TGF-β3) is a member of the TGF-beta superfamily, which plays a crucial role in various biological processes, including cell growth, differentiation, apoptosis, and tissue repair. Research has revealed that TGF-β3 is particularly important in wound healing, fibrosis, and embryonic development. Its unique regulatory functions suggest potential therapeutic applications in tissue regeneration and remodeling. Recombinant TGF-β3 protein has garnered attention due to its ability to modulate cellular responses and promote collagen synthesis, making it a candidate for use in regenerative medicine and reconstructive surgery. Studies indicate that TGF-β3 can enhance the healing of skin, cartilage, and bone, leading to its exploration in clinical settings for conditions such as chronic wounds and degenerative diseases. However, the precise mechanisms of TGF-β3 action remain to be fully elucidated, prompting further investigation into its signaling pathways and interactions with other molecules in the extracellular matrix. Additionally, researchers are exploring the optimization of recombinant production techniques to improve yield and bioactivity, as well as strategies for delivering TGF-β3 effectively to target tissues. The ongoing research into TGF-β3 not only aims to clarify its biological functions but also seeks to translate these findings into innovative therapeutic solutions for patients suffering from various tissue injuries and disorders. Overall, the study of TGF-β3 recombinant protein represents a promising frontier in the quest for advanced regenerative therapies.
