Analytical Data
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基因名
TCEA2
- Application
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别名
TCEA2;Transcription elongation factor A Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15560
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表达区间
1-299aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMMGKEEEIARIARRLDKMVTKKSAEGA MDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWK KLLDASDAKARERGRGMPLPTSSRDASEAPDPSRKRPELPRAPSTPRITT FPPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRD VGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMA SDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTR SSDEPMTTFVVCNECGNRWKFC
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TCEA2, or Transcription Elongation Factor A (SII), is a crucial protein involved in the regulation of RNA polymerase II transcription elongation. Research into TCEA2 has gained importance due to its role in the transcriptional machinery, where it influences mRNA synthesis and processing. Dysregulation of TCEA2 has been implicated in various cellular processes, including cell proliferation and differentiation, making it a potential target for understanding diseases such as cancer. Recent studies have focused on the characterization and recombinant expression of TCEA2 to explore its functional mechanisms and interactions with other transcription factors. The ability to produce TCEA2 as a recombinant protein enables researchers to examine its structural properties, post-translational modifications, and binding affinities, which are critical for elucidating its role in transcription regulation. Moreover, understanding the functional dynamics of TCEA2 could provide insights into therapeutic strategies aimed at modulating gene expression in pathological conditions. As a result, the ongoing investigation into the biochemical and biological properties of TCEA2 is pivotal for expanding our knowledge of gene regulation and the development of targeted interventions in diseases associated with transcriptional dysregulation.












