Analytical Data
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基因名
ALS2CR7
- Application
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别名
CDK15; ALS2CR7; PFTK2Cyclin-dependent kinase 15; EC 2.7.11.22
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96Q40
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表达区间
1-349aa
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氨基酸序列
MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE
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分子量
66 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ALS2CR7 is a gene located on human chromosome 7 that encodes a protein involved in multiple cellular processes, including endosomal trafficking and neuronal function. Research into ALS2CR7 has gained momentum due to its association with various neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS) and certain types of hereditary spastic paraplegia. Understanding the structure and function of ALS2CR7 and its protein product is crucial for elucidating the molecular mechanisms underlying these disorders. Experimental approaches, including the production of recombinant ALS2CR7 protein, have been employed to investigate its biochemical properties and functional roles in cell signaling and protein interactions. Insights gained from these studies could pave the way for novel therapeutic strategies targeting ALS2CR7-related pathways. Furthermore, the exploration of ALS2CR7’s role in neurodegeneration may contribute to a broader understanding of the pathophysiology of ALS and enhance the development of diagnostic tools, potentially benefiting affected individuals and their families.
