Analytical Data
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Gene name
ALS2CR11
- Application
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Alternative Names
C2CD6; ALS2CR11C2 calcium-dependent domain-containing Protein 6
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q53TS8
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Expression Region
1-623aa
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AA Sequence
MEPPQETNRPFSTLDNRSGQVQVLSATPLLQRNPYSSPDIMHIKGSEASSVPYALNQGTTALPKNKNQEGTGHRLLNMLRKTLKESDSEELEITQETPNLVPFGDVVGCLGIHIKNCRHFMPKISLQHYANLFIRISINKAVKCTKMCSLLSKNDEKNTVIKFDEVKYFSVQVPRRYDDKRNNILLELIQYDNREKRAFLLGSVQIHLYEVIQKGCFIEEVQVLHGNIFVCRLEVEFMFSYGNFGYGFSHQLKPLQKITEPSMFMNLAPPPERTDPVTKVITPQTVEYPAFLSPDLNVTVGTPAVQSSNQPSVVRLEKLQQQPRERLEKMKKEYRNLNTWIDKANYLESILMPKLEHKDSEETNIDEASENTKSNQPEEELENIVGVDIPLVNEEAETTANELLDNDSEKGLTIPTLNQSDQDNSTADASKNDESTPSPTEVHSLCTISNQETIKAGRIPPLGERQSESMPDRKMKNVFFPLEVKLKDNYPSILKADSSLSEVAFSPKEYNSPSFRPEYIEFKPKFQDCSDKFEDLHDMTSFTHLKKVKSRSRLLGKSSDDIHNHARHSARPYTAPEVNKQRESYSGKFTSRRMVSSGLVHINDKTSDYEMHKMRPKKIKRGY
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Molecular Weight
97.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ALS2CR11 is a novel protein encoded by the ALS2CR11 gene, which has drawn attention in recent years due to its potential role in various biological processes and diseases. This protein is thought to be involved in neuronal function and the regulation of cellular interactions, particularly in relation to neurodegenerative disorders. Research indicates that ALS2CR11 may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS) and other motor neuron diseases, given its expression in the nervous system. Moreover, studies have suggested a possible involvement of ALS2CR11 in the regulation of synaptic stability and neuronal survival. Understanding the structure and function of ALS2CR11 through recombinant protein studies offers insights into its mechanistic roles in neuronal signaling and cellular pathways. Furthermore, ALS2CR11 serves as a promising target for therapeutic interventions aimed at mitigating the effects of neurodegenerative conditions. Through elucidating the molecular mechanisms associated with ALS2CR11, researchers hope to uncover novel strategies for disease prevention and treatment in the field of neurology. The ongoing investigation into ALS2CR11 not only enhances our understanding of neurobiology but also paves the way for the development of targeted therapies that could significantly improve patient outcomes in diseases associated with neuronal dysfunction.
