Analytical Data
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Gene name
OSBPL9
- Application
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Alternative Names
OSBPL9；ORP9；OSBP4；Oxysterol-binding Protein-related Protein 9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96SU4
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Expression Region
1-558aa
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AA Sequence
MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQ LCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNL SPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGN SLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHL LSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKD RMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSK FLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECN INCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGV MYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKI RDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLL KRLGAAKH
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Molecular Weight
83.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OSBPL9 (Oxysterol Binding Protein-Like 9) is a member of the OSBP family, which is known to play a crucial role in lipid metabolism and cellular signaling. Research into OSBPL9 has garnered attention due to its implication in various physiological processes and diseases, including cancer, cardiovascular disorders, and metabolic syndromes. It is thought to interact with oxysterols, which are oxidized derivatives of cholesterol, and other lipid signaling molecules, potentially influencing cellular functions such as membrane dynamics, inflammation, and apoptosis. Studies suggest that OSBPL9 may also be involved in the regulation of lipid droplet metabolism and endoplasmic reticulum stress response. As a result, the expression and activity of OSBPL9 have become a focal point for understanding how dysregulation of lipid homeostasis can lead to pathological conditions. Recent advancements in recombinant protein technologies have enabled researchers to produce OSBPL9 in various systems, facilitating detailed functional studies and the exploration of its structural properties. Investigating the recombinant form of OSBPL9 not only aids in elucidating its biological functions but also holds promise for therapeutic interventions that leverage its role in lipid signaling pathways. This line of research is critical in identifying novel biomarkers for disease and developing targeted treatments that can modulate OSBPL9 activity for potential clinical applications.
