Analytical Data
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基因名
FOXF1
- Application
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别名
FOXF1；FKHL5；FREAC1；Forkhead box Protein F1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q12946
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表达区间
1-379aa
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氨基酸序列
MSSAPEKQQP PHGGGGGGGG GGGAAMDPAS SGPSKAKKTN AGIRRPEKPP YSYIALIVMA IQSSPTKRLT LSEIYQFLQS RFPFFRGSYQ GWKNSVRHNL SLNECFIKLP KGLGRPGKGH YWTIDPASEF MFEEGSFRRR PRGFRRKCQA LKPMYSMMNG LGFNHLPDTY GFQGSAGGLS CPPNSLALEG GLGMMNGHLP GNVDGMALPS HSVPHLPSNG GHSYMGGCGG AAAGEYPHHD SSVPASPLLP TGAGGVMEPH AVYSGSAAAW PPSASAALNS GASYIKQQPL SPCNPAANPL SGSLSTHSLE QPYLHQNSHN APAELQGIPR YHSQSPSMCD RKEFVFSFNA MASSSMHSAG GGSYYHQQVT YQDIKPCVM
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分子量
40.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOXF1 (Forkhead Box F1) is a transcription factor that plays a crucial role in various biological processes, including cellular differentiation, proliferation, and organogenesis. Research has shown that FOXF1 is particularly important in the development of the lungs and other organs, where it regulates the expression of genes involved in tissue formation and function. Abnormal expression of FOXF1 has been linked to several developmental disorders, particularly congenital diseases affecting the respiratory system, such as alveolar capillary dysplasia. Studies have demonstrated that FOXF1 can influence endothelial cell function and is vital for maintaining the structural integrity of the lung vasculature. Given its significance, there is a growing interest in the generation of FOXF1 recombinant proteins to better understand its molecular mechanisms and to explore potential therapeutic applications. By producing and characterizing FOXF1 recombinant proteins, researchers aim to elucidate its interactions with other proteins and pathways, providing insights into its role in health and disease. The study of FOXF1 is essential for uncovering the underlying mechanisms of various disorders and may lead to novel strategies for treatment, particularly in congenital respiratory conditions.
