Analytical Data
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基因名
SYCE3
- Application
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别名
SYCE3;C22orf41;Synaptonemal complex central element Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A1L190
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表达区间
1-88aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MDDADPEERN YDNMLKMLSD LNKDLEKLLE EMEKISVQAT WMAYDMVVMR TNPTLAESMR RLEDAFVNCK EEMEKNWQEL LHETKQRL
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分子量
13 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SYCE3, a crucial protein involved in the formation of the synaptonemal complex during meiosis, has garnered significant attention in recent years due to its pivotal role in ensuring proper chromosome pairing and segregation. Meiosis is a specialized form of cell division that reduces chromosome number in gametes, and any disruption in this process can lead to infertility, aneuploidies, or developmental disorders. SYCE3 is known to interact with various other proteins in the synaptonemal complex, facilitating the structural organization necessary for homologous chromosome alignment. Studies have shown that mutations or aberrations in the SYCE3 gene can lead to compromised meiotic function and associated reproductive challenges. Consequently, research efforts have focused on the detailed characterization of SYCE3's structure, function, and interaction networks, employing techniques such as recombinant protein expression, molecular modeling, and biochemical assays. Understanding how SYCE3 operates within the meiotic pathway is vital for elucidating the underlying mechanisms of meiosis and could provide insights into potential therapeutic targets for infertility treatments and genetic disorders linked to chromosomal abnormalities. As such, the ongoing investigation into SYCE3's role is not only relevant for basic biology but also holds substantial implications for reproductive health and genetic research.












