Analytical Data
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基因名
GATA5
- Application
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别名
GATA5；Transcription factor GATA-5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BWX5
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表达区间
1-397aa
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氨基酸序列
MYQSLALAAS PRQAAYADSG SFLHAPGAGS PMFVPPARVP SMLSYLSGCE PSPQPPELAA RPGWAQTATA DSSAFGPGSP HPPAAHPPGA TAFPFAHSPS GPGSGGSAGG RDGSAYQGAL LPREQFAAPL GRPVGTSYSA TYPAYVSPDV AQSWTAGPFD GSVLHGLPGR RPTFVSDFLE EFPGEGRECV NCGALSTPLW RRDGTGHYLC NACGLYHKMN GVNRPLVRPQ KRLSSSRRAG LCCTNCHTTN TTLWRRNSEG EPVCNACGLY MKLHGVPRPL AMKKESIQTR KRKPKTIAKA RGSSGSTRNA SASPSAVAST DSSAATSKAK PSLASPVCPG PSMAPQASGQ EDDSLAPGHL EFKFEPEDFA FPSTAPSPQA GLRGALRQEA WCALALA
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分子量
41.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GATA5 is a member of the GATA family of transcription factors, which play crucial roles in various biological processes, including development, differentiation, and tissue homeostasis. During embryonic development, GATA5 is particularly important in cardiac and intestinal morphogenesis, as it regulates genes critical for these processes. Dysregulation of GATA5 expression has been implicated in various diseases, including congenital heart defects and certain types of cancer. Research has shown that GATA5 participates in the regulation of lineage specification and angiogenesis, making it a potential target for therapeutic interventions. The study of GATA5 recombinant proteins is essential for understanding its structure-function relationships, post-translational modifications, and interaction with other molecular partners in cellular pathways. By producing GATA5 as a recombinant protein, scientists can investigate its function in vitro, allowing for the detailed characterization of its enzymatic properties and the identification of binding partners, ultimately contributing to the elucidation of its role in both normal physiology and disease states. The ongoing research into GATA5’s mechanisms of action and its potential as a biomarker or therapeutic target highlights its importance in regenerative medicine and cancer therapy, thereby underscoring the significance of continued investigation in this area.
