Analytical Data
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Gene name
STX12
- Application
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Alternative Names
STX12；Syntaxin-12
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86Y82
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Expression Region
1-248aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDS SKLQENLQQL QHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSE KEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADIL DVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX12, or Syntaxin 12, is a member of the syntaxin family of proteins, which play critical roles in the membrane fusion processes essential for intracellular transport and secretion. Research into STX12 has garnered interest due to its involvement in various cellular functions, including endocytosis and exocytosis, as well as its potential links to several diseases. Studies suggest that STX12 is particularly important in immune responses, where it may be implicated in the regulation of vesicle trafficking and cytokine secretion in immune cells. Investigating STX12 can provide insights into molecular mechanisms underlying immune system regulation and may reveal novel therapeutic targets for conditions such as autoimmune diseases and cancer. Additionally, the exploration of STX12’s interactions with other proteins in the SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex could enhance our understanding of how intracellular transport processes are coordinated. As a recombinant protein, STX12 can be produced and studied in vitro to dissect its functional properties and interactions, thereby contributing to a more comprehensive understanding of its biological significance. The relevance of STX12 in both basic cellular functions and pathological conditions underscores the importance of this research, paving the way for advancements in targeted therapies and biotechnology applications.
