Analytical Data
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Gene name
AGPAT6
- Application
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Alternative Names
GPAT4; AGPAT6; TSARG7; UNQ551/PRO1108; Glycerol-3-phosphate acyltransferase 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86UL3
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Expression Region
1-78.5aa
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AA Sequence
MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLRMERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRIALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS
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Molecular Weight
52 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AGPAT6, or 1-Acylglycerol-3-phosphate O-acyltransferase 6, is an enzyme that plays a crucial role in lipid metabolism and is involved in the synthesis of phospholipids and triglycerides, essential components of cellular membranes and energy storage. Research into AGPAT6 has gained significant attention due to its implications in metabolic disorders, including obesity, diabetes, and cardiovascular diseases. As AGPAT6 influences the production of diacylglycerol, its activity is closely linked to cellular signaling pathways that regulate lipid accumulation and insulin sensitivity. Understanding the structure and function of AGPAT6 can provide insights into the mechanisms of lipid-related diseases and aid in the development of targeted therapies. Furthermore, the generation of recombinant AGPAT6 protein allows researchers to study its enzymatic properties, substrate specificity, and interaction with other cellular components in controlled laboratory settings. By investigating the molecular mechanisms underlying AGPAT6 regulation and function, scientists aim to uncover potential biomarkers for early diagnosis and novel intervention strategies for metabolic syndromes. This growing body of research underscores the significance of AGPAT6 in maintaining lipid homeostasis and highlights its potential as a therapeutic target in combating metabolic diseases.
