Analytical Data
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基因名
AGPAT1
- Application
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别名
AGPAT1; G15; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99943
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表达区间
1-283aa
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氨基酸序列
MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
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分子量
58.1 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1) is an essential enzyme involved in glycerolipid metabolism, playing a crucial role in the synthesis of triglycerides and phospholipids. Mutations in the AGPAT1 gene are linked to various metabolic disorders, particularly serious conditions such as congenital lipodystrophy, which is characterized by an abnormal distribution of body fat and severe insulin resistance. The study of AGPAT1 recombinant protein has gained significant attention in recent years as researchers strive to understand its function and regulation in lipid metabolism and energy homeostasis. By producing AGPAT1 as a recombinant protein, scientists can investigate its enzymatic activity, interaction with other proteins, and potential regulatory mechanisms at the molecular level. This understanding can lead to insights into the pathophysiology of lipid-related diseases and may pave the way for developing therapeutic strategies aimed at treating metabolic disorders associated with AGPAT1 dysfunction. Thus, research on AGPAT1 recombinant protein not only contributes to our fundamental knowledge of lipid biochemistry but also holds promise for advancing medical interventions for metabolic syndromes.
