Cat: PA2000-5329

Recombinant Human ACRBP Protein,His

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Analytical Data

  • Gene name

    ACRBP

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ACRBP; ACRBP_HUMAN; acrosin binding Protein; Acrosin binding Protein precursor

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NEB7

  • Expression Region

    26-543aa

  • AA Sequence

    QDSTQ ASTPGSPLSP TEYERFFALL TPTWKAETTC RLRATHGCRN PTLVQLDQYE NHGLVPDGAV CSNLPYASWF ESFCQFTHYR CSNHVYYAKR VLCSQPVSIL SPNTLKEIEA SAEVSPTTMT SPISPHFTVT ERQTFQPWPE RLSNNVEELL QSSLSLGGQE QAPEHKQEQG VEHRQEPTQE HKQEEGQKQE EQEEEQEEEG KQEEGQGTKE GREAVSQLQT DSEPKFHSES LSSNPSSFAP RVREVESTPM IMENIQELIR SAQEIDEMNE IYDENSYWRN QNPGSLLQLP HTEALLVLCY SIVENTCIIT PTAKAWKYME EEILGFGKSV CDSLGRRHMS TCALCDFCSL KLEQCHSEAS LQRQQCDTSH KTPFVSPLLA SQSLSIGNQV GSPESGRFYG LDLYGGLHMD FWCARLATKG CEDVRVSGWL QTEFLSFQDG DFPTKICDTD YIQYPNYCSF KSQQCLMRNR NRKVSRMRCL QNETYSALSP GKSEDVVLRW SQEFSTLTLG QFG

  • Molecular Weight

    61.3 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ACRBP (Ankyrin-Repeat Containing Protein), a member of the ankyrin-repeat family, has garnered significant interest in recent years due to its potential roles in various biological processes and diseases. Initially identified as a protein involved in intracellular signaling pathways and protein-protein interactions, ACRBP has been implicated in regulating cell cycle progression, apoptosis, and stress responses. Its expression levels have been associated with several cancers, suggesting that ACRBP could serve as a biomarker for tumor progression and a potential therapeutic target. Researchers have sought to understand the structural and functional dynamics of ACRBP through recombinant protein studies, allowing them to elucidate its mechanisms of action and interactions with other cellular components. The use of recombinant DNA technology has enabled the production of ACRBP in various expression systems, facilitating studies on its biochemical properties, interaction networks, and effects on cellular functions. This research is crucial for uncovering the role of ACRBP in health and disease, paving the way for novel approaches in cancer therapy and other related fields. As such, ACRBP represents a promising focus of study within molecular biology and biomedical research, helping to bridge the gap between fundamental biology and potential clinical applications.

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