Analytical Data
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基因名
ODF2L
- Application
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别名
ODF2L; BCAP; KIAA1229; Protein BCAP; Basal body centriole-associated protein; Outer dense fiber protein 2-like
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ULJ1
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表达区间
1-636 aa
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氨基酸序列
MEKAVNDGSH SEELFCHLKT ISEKEDLPRC TSESHLSCLK QDILNEKTEL EATLKEAELV THSVELLLPL FKDTIEKINF ENANLSALNL KISEQKEILI KELDTFKSVK LALEHLLRKR DYKQTGDNLS SMLLENLTDN ESENTNLKKK VFEKEAHIQE LSCLFQSEKA NTLKANRFSQ SVKVVHERLQ IQIHKREAEN DKLKEYVKSL ETKIAKWNLQ SRMNKNEAIV MKEASRQKTV ALKKASKVYK QRLDHFTGAI EKLTSQIRDQ EAKLSETISA SNAWKSHYEK IVIEKTELEV QIETMKKQII NLLEDLKKME DHGKNSCEEI LRKVHSIEYE NETLNLENTK LKLRFPCRIT ESKNMNILIV LDMLCYISSE KTTLAALKDE VVSVENELSE LQEVEKKQKT LIEMYKTQVQ KLQEAAEIVK SRCENLLHKN NQITKTKNKN VEKMRGQMES HLKELERVCD SLTAAERRLH ECQESLQCCK GKCADQEHTI RELQGQVDGN HNLLTKLSLE EENCLIQLKC ENLQQKLEQM DAENKELEKK LANQEECLKH SNLKFKEKSA EYTALARQLE AALEEGRQKV AEEIEKMSSR ESALQIKILD LETELRKKNE EQNQLVCKMN SDPETP
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分子量
73.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ODF2L (Outer Dense Fiber 2-Like) is a vital protein that plays a critical role in the formation and stability of the outer dense fibers of sperm flagella, which are essential for sperm motility and fertility. Research on ODF2L has gained momentum due to its implications in reproductive biology, particularly in understanding male infertility. Studies have shown that decreased expression or mutations in the ODF2L gene can lead to structural defects in sperm, resulting in impaired motility and, consequently, infertility. The protein’s unique structure and function make it a compelling target for recombinant protein studies, enabling scientists to elucidate its biochemical properties and interactions within the sperm flagellum. In addition to its role in fertility, emerging evidence suggests that ODF2L may also be implicated in other cellular processes, including ciliogenesis and cell signaling pathways, broadening its significance beyond reproductive health. As our understanding of the molecular mechanisms behind ODF2L functions advances, it may pave the way for novel therapeutic strategies to address male infertility and associated disorders. Therefore, the study of ODF2L recombinant proteins not only enhances our comprehension of sperm biology but also presents opportunities for innovative interventions in reproductive medicine.
